A 3-Year-Old Boy Is Brought to the Office with 5

question 199

Multiple Choice

A 3-year-old boy is brought to the office with 5 days of productive cough and fever.  Examination shows a tachypneic, ill-appearing child with rales over the right lower lung.  Chest x-ray reveals right lower lobe pneumonia.  The boy is admitted to the hospital for intravenous antibiotics.  Review of his medical history shows 4 prior pneumonias, and his weight is at the third percentile.  Further testing demonstrates high sweat chloride content, and genetic sequencing shows a mutation in a transmembrane protein.  Which of the following best describes the dysfunctional transmembrane protein causing this patient's disease?

• A)ATP-gated
• B)Cyclic nucleotide-gated
• C)Mechanically gated
• D)Temperature-gated
• E)Voltage-gated

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Soviet Union

A former federal socialist state in Eastern Europe and Northern Asia, existing from 1922 to 1991, known officially as the Union of Soviet Socialist Republics (USSR).

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