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Researchers Are Testing Various Modalities to Reduce Glutamate-Induced Excitotoxic Neuronal

question 7

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Researchers are testing various modalities to reduce glutamate-induced excitotoxic neuronal injury after ischemic stroke.  The investigators record the postsynaptic potential of cortical neurons under various conditions.  The neurons are exposed to glutamate, which causes them to depolarize; excessive depolarization triggers cell death.  The experiment is repeated after altering the electrolyte composition of the extracellular fluid.  When the extracellular magnesium concentration is increased, glutamate-induced neuron depolarization and cell death are decreased.  Which of the following changes in ion conductance explains the improved neuron survival in response to magnesium?


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Lipoma

A benign tumor composed of adipose tissue (body fat) that is usually not harmful and can occur in any part of the body.

Benign

Describing a condition, tumor, or growth that is not cancerous and is less likely to pose a serious threat to health.

Arteriosclerotic Heart Disease

A form of heart disease caused by the hardening and narrowing of the arteries, affecting blood flow.

Medical Abbreviation

Shortened forms of words or phrases used in medical contexts to save time and space in documentation.

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