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A 67-Year-Old Man Comes to the Emergency Department Due to 2

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A 67-year-old man comes to the emergency department due to 2 days of fever, malaise, headache, and myalgia.  He has also noticed a nonpruritic skin rash on his right leg.  The patient has had no abdominal pain, vomiting, or diarrhea.  Prior medical problems include hypertension, type 2 diabetes mellitus, and chronic obstructive pulmonary disease.  He is an ex-smoker and does not use alcohol or illicit drugs.  The patient lives in Texas and a week ago returned from visiting family in Connecticut, where he spent most of his time outdoors.
Temperature is 39.4 C (103 F), blood pressure is 124/84 mm Hg, pulse is 102/min, and respirations are 20/min.  Examination shows no scleral icterus or lymphadenopathy.  Breath sounds are mildly decreased throughout.  The abdomen is soft with no hepatosplenomegaly.  There is no neck stiffness.  A 4-cm, erythematous skin rash with central clearing is present on the right popliteal area.
Laboratory results are as follows:
A 67-year-old man comes to the emergency department due to 2 days of fever, malaise, headache, and myalgia.  He has also noticed a nonpruritic skin rash on his right leg.  The patient has had no abdominal pain, vomiting, or diarrhea.  Prior medical problems include hypertension, type 2 diabetes mellitus, and chronic obstructive pulmonary disease.  He is an ex-smoker and does not use alcohol or illicit drugs.  The patient lives in Texas and a week ago returned from visiting family in Connecticut, where he spent most of his time outdoors. Temperature is 39.4 C (103 F), blood pressure is 124/84 mm Hg, pulse is 102/min, and respirations are 20/min.  Examination shows no scleral icterus or lymphadenopathy.  Breath sounds are mildly decreased throughout.  The abdomen is soft with no hepatosplenomegaly.  There is no neck stiffness.  A 4-cm, erythematous skin rash with central clearing is present on the right popliteal area. Laboratory results are as follows:   Chest x-ray reveals no parenchymal opacity or pleural effusion. Which of the following diagnostic studies is most appropriate for this patient? A)Anti-parvovirus antibodies B)Antirickettsial antibodies C)Bone marrow biopsy D)Borrelia burgdorferi serology E)Peripheral blood microscopy Chest x-ray reveals no parenchymal opacity or pleural effusion.
Which of the following diagnostic studies is most appropriate for this patient?
A)Anti-parvovirus antibodies
B)Antirickettsial antibodies
C)Bone marrow biopsy
D)Borrelia burgdorferi serology
E)Peripheral blood microscopy

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