A Large Multicenter Double-Blinded Randomized Placebo-Controlled Study Is Being Planned

question 863

Multiple Choice

A large multicenter double-blinded randomized placebo-controlled study is being planned to evaluate a new medication.  Primary endpoints addressing mortality benefits are chosen, and a comprehensive analysis strategy is specified, including for predefined subgroups.
In discussing the advantages of this study design, which of the following represents a benefit of randomization?

• A)Randomization can be performed at the level of subgroup analysis
• B)Randomization distributes known and unknown variables equally among the study groups
• C)Randomization ensures that the study results are statistically significant
• D)Randomization ensures that the study sample is representative of the population
• E)Randomization prevents group allocation concealment from study participants and investigators

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Definitions:

Socialization

encompasses the process by which individuals learn the norms, values, and required behaviors of a society or specific group.

Kinds Of Fit

This can refer to how well individuals match with their job, organization, or team in terms of values, skills, and characteristics, enhancing performance and satisfaction.

Expectations

Assumptions or beliefs about what will happen in the future or how someone should behave.

Organizations

Structured groups of individuals working together to achieve common goals.