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A 42-Year-Old Woman Comes to the Office Due to a Rash

question 401

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A 42-year-old woman comes to the office due to a rash.  She has experienced recurring "red spots" on her legs for 2-3 years.  These appear sporadically, last a few weeks to a few months, and disappear spontaneously.  The rash is not pruritic.  When it occurs, the patient also experiences generalized fatigue and arthralgias involving her hips and knees.  She rarely has right lower quadrant pain with the rash.  Review of systems is otherwise normal.
Medical history is unremarkable.  The patient has no known drug allergies.  Her only medication is an oral contraceptive, which she has taken for several years.  She does not use tobacco, alcohol, or illicit drugs.  She is single and works in an office.
On examination, the patient appears healthy.  Blood pressure is 136/86 mm Hg, pulse is 72/min, and respirations are 14/min.  BMI is 24 kg/m2.  Physical examination is normal except for the skin.  A total of 10-12 palpable red lesions, measuring 1×0.5 cm, are scattered over both lower extremities distal to the mid-calf.  The lesions are nontender and do not blanch with pressure.
Laboratory results are as follows:
A 42-year-old woman comes to the office due to a rash.  She has experienced recurring  red spots  on her legs for 2-3 years.  These appear sporadically, last a few weeks to a few months, and disappear spontaneously.  The rash is not pruritic.  When it occurs, the patient also experiences generalized fatigue and arthralgias involving her hips and knees.  She rarely has right lower quadrant pain with the rash.  Review of systems is otherwise normal. Medical history is unremarkable.  The patient has no known drug allergies.  Her only medication is an oral contraceptive, which she has taken for several years.  She does not use tobacco, alcohol, or illicit drugs.  She is single and works in an office. On examination, the patient appears healthy.  Blood pressure is 136/86 mm Hg, pulse is 72/min, and respirations are 14/min.  BMI is 24 kg/m<sup>2</sup>.  Physical examination is normal except for the skin.  A total of 10-12 palpable red lesions, measuring 1×0.5 cm, are scattered over both lower extremities distal to the mid-calf.  The lesions are nontender and do not blanch with pressure. Laboratory results are as follows:   Which of the following would most likely be found in this patient? A) Anti-double-stranded DNA antibodies B) Anti-hepatitis C virus antibodies C) Anti-Ro antibodies D) Capillary IgA deposits on skin biopsy E) Focal glomerular sclerosis on renal biopsy Which of the following would most likely be found in this patient?


Definitions:

Drug-Free Screenings

Procedures to test individuals for the absence of illicit drugs or substances in their system, typically used in employment or legal settings.

Community-Based

Pertaining to services or activities that are located within and designed to serve a particular local community.

Cash Prizes

Monetary awards given to contestants or participants in competitions, contests, or sweepstakes as a form of incentive or reward.

Campus Arrests

Detentions or apprehensions occurring on college or university grounds, typically by campus security or local law enforcement.

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