A 40-Year-Old Man Is Found to Have Severe Hypertriglyceridemia on Routine

question 1047

Multiple Choice

A 40-year-old man is found to have severe hypertriglyceridemia on routine evaluation.  He has no present complaints.  Medical history includes hypertension controlled with hydrochlorothiazide and asymptomatic gallstones.  His father had a nonfatal myocardial infarction at age 47.  The patient does not smoke or consume alcohol.  Blood pressure is 130/75 mm Hg and pulse is 70/min.  He is prescribed niacin for his hypertriglyceridemia.  The patient returns 1 week later due to intense, generalized pruritus and flushing.  What is the most likely cause of his complaint?

• A)Hypersensitivity reaction
• B)Prostaglandin-related reaction
• C)Drug-drug interaction
• D)Drug-induced vasoconstriction
• E)Psychogenic reaction

---

Definitions:

Keratin

A type of protein found in the skin, hair, and nails, responsible for their strength, protection, and waterproofing properties.

Waterproofing

The process of making an object or structure resistant to water penetration.

Mucus

A sticky, thick fluid secreted by mucous membranes and glands, providing lubrication and protection in various parts of the body.

Gas Exchange

The biological process through which organisms exchange oxygen and carbon dioxide with their environment, essential for respiration.