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A 71-year-old man is brought to the office by his daughter due to a change in behavior over the past year. He began having memory problems several years ago and frequently forgot his grandchildren's names. Also, the patient often had difficulty finding words. Several times recently, he was found roaming his apartment building because he was lost. The patient insists that there is nothing wrong with him and jokingly makes excuses for the symptoms his daughter is reporting. He has never used alcohol or illicit drugs. Blood pressure is 155/85 mm Hg, pulse is 90/min, and respirations are 15/min. Plantar reflexes are downgoing bilaterally. The remainder of the neurologic examination is within normal limits. Montreal Cognitive Assessment score is 15 on a scale of 30 (normal: ≥26) . Laboratory results are as follows: Which of the following abnormalities is most likely to be seen on this patient's MRI?
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