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A 1-month-old boy is brought to the emergency department by his mother due to fussiness and vomiting. Three days ago, the patient vomited after being laid down for a nap. The vomitus was not bloody or bilious. The mother thought the vomiting was due to gastroesophageal reflux and kept the infant upright after his next feedings. However, he continued to vomit several times a day and today has been difficult to console. Urine output remains normal. The patient was born at home via spontaneous vaginal delivery and is exclusively breastfed. He has received no vaccinations or medications. Temperature is 37.4 C (99.3 F) . Vital sign measurement also reveals intermittent bradycardia and hypertension. The anterior fontanelle is bulging. Eye examination shows a persistent downward gaze bilaterally. Cardiac examination reveals no murmurs. Extremities appear normal. Head imaging is as shown: Which of the following is the most likely cause of this patient's presentation?
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