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A 4-Month-Old Boy Is Brought to the Emergency Department Due

question 94

Multiple Choice

A 4-month-old boy is brought to the emergency department due to 5 days of fever, cough, and shortness of breath.  The patient was born at 38 weeks gestation via uncomplicated vaginal delivery.  At age 2 months, he was diagnosed with cervical lymphadenitis that required prolonged oral antibiotics.  Temperature is 38.5 C (101.3 F) , blood pressure is 80/40 mm Hg, pulse is 120/min, and respirations are 40/min.  Oxygen saturation is 95% on room air.  The patient is alert and responsive.  Oropharyngeal examination shows no abnormalities.  Mild chest retraction and bilateral rales are present.  Chest x-ray reveals bilateral pulmonary infiltrates.  The patient is given appropriate empiric antibiotic therapy for pneumonia; however, after 3 days, he continues to be febrile and laboratory assessment shows increased leukocyte count.  CT scan of the chest shows multifocal pneumonia with areas of cavitation.  Cultures obtained via bronchoalveolar lavage grow a filamentous, gram-positive rod consistent with Nocardia infection.  Immunodeficiency is suspected.  Which of the following tests would most likely identify the underlying immune disorder in this patient?

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Definitions:

Predictive Validity

The extent to which a test accurately forecasts a specific future outcome.

Concurrent Validity

The degree to which the results of a particular test correlate with those of another established measure given at the same time.

Reliability

The consistency and dependability of a measure or test over time, ensuring that similar results are achieved under consistent conditions.

Standard Deviation

A statistical measure of the dispersion or variation in a set of values, indicating how much individual data points differ from the mean value.

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