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A 3-Year-Old Boy Is Brought to the Emergency Department Due

question 200

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A 3-year-old boy is brought to the emergency department due to a 3-day history of fever, vomiting, and diarrhea.  His mother reports that his urine output has decreased over the last day.  She has been giving him ibuprofen for fever, which has improved intermittently.  The patient has no chronic medical conditions and takes no daily medications.  Temperature is 38.3 C (100.9 F) , blood pressure is 82/60 mm Hg, pulse is 144/min, and respirations are 24/min.  Examination shows dry lips and mucous membranes.  The abdomen has mild, diffuse tenderness, and bowel sounds are hyperactive.  Capillary refill is 4 seconds.  The remainder of the examination shows no abnormalities.  Laboratory results are as follows: A 3-year-old boy is brought to the emergency department due to a 3-day history of fever, vomiting, and diarrhea.  His mother reports that his urine output has decreased over the last day.  She has been giving him ibuprofen for fever, which has improved intermittently.  The patient has no chronic medical conditions and takes no daily medications.  Temperature is 38.3 C (100.9 F) , blood pressure is 82/60 mm Hg, pulse is 144/min, and respirations are 24/min.  Examination shows dry lips and mucous membranes.  The abdomen has mild, diffuse tenderness, and bowel sounds are hyperactive.  Capillary refill is 4 seconds.  The remainder of the examination shows no abnormalities.  Laboratory results are as follows:   Which of the following is the most likely cause of this patient's decreased urine output? A) Drug-induced interstitial nephritis B) Immune complex deposition C) Renal vasoconstriction D) Thrombotic microangiopathy E) Toxin-mediated renal tubular injury Which of the following is the most likely cause of this patient's decreased urine output?


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