A 49-Year-Old Woman Comes to the Office Due to Depression

question 15

Multiple Choice

A 49-year-old woman comes to the office due to depression.  She quit her retail sales job 6 months ago as she could no longer stand all day due to increasing numbness, tingling, and painful, burning sensations in her feet.  The patient has since become increasingly depressed, withdrawn, and preoccupied with feelings of low self-esteem.  She is unable to concentrate to read or watch television and has lost interest in her family and friends.  The patient also describes severe insomnia and extremely low energy.  Medical history is significant for obesity, hypercholesterolemia, and type 2 diabetes mellitus.  Medications include glipizide and lisinopril.  She has no prior psychiatric history.  After medical evaluation, major depressive disorder is diagnosed.  Which of the following is the most appropriate pharmacotherapy to treat this patient's condition?

• A)Bupropion
• B)Citalopram
• C)Duloxetine
• D)Mirtazapine
• E)Trazodone