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An imaging study detects an incidental 3.5-cm infrarenal abdominal aortic aneurysm in a 70-year-old man. He has no associated symptoms. Medical history is significant for hypertension, type 2 diabetes, and hypercholesterolemia. The patient is maintained on anticoagulation due to paroxysmal atrial fibrillation. He has smoked 1-2 packs of cigarettes a day for the past 40 years, and he drinks 1 or 2 glasses of wine daily. The patient is physically active, bikes regularly, and enjoys hiking. On physical examination, blood pressure is 150/78 mm Hg and pulse is 80/min. Heart sounds are normal, and the lungs are clear. Laboratory results are as follows: Which of the following is most strongly associated with aneurysm progression in this patient?
Principal-Agent Problem
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