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A 34-Year-Old Man Comes to the Emergency Department Due to Acute-Onset

question 416

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A 34-year-old man comes to the emergency department due to acute-onset central chest and epigastric pain radiating to the mid-lower back.  The pain started an hour ago while at rest.  The patient also reports mild shortness of breath and diaphoresis.  He has not seen a physician in 10 years.  The patient drinks 3 or 4 beers most days and occasionally uses cocaine.  His last use of cocaine was a day ago.  On examination, the patient is in severe distress due to pain.  Skin is cool and clammy.  Blood pressure is 210/120 mm Hg and equal in both arms.  Pulse is 110/min and regular, and respirations are 22/min.  Pulse oximetry shows 95% on room air.  BMI is 34 kg/m2.  There is no pulse asymmetry.  Jugular venous pressure is normal.  Breath sounds are decreased at the left lower base, and percussion is dull in the same area.  Heart sounds are normal with no murmurs or extra sounds.  Abdominal and neurologic examinations show no abnormalities.  Extremities have no cyanosis, clubbing, or edema.  ECG reveals sinus tachycardia with nonspecific T-wave changes.  Serum troponin is normal.  D-dimer is elevated.  Serum lipase is normal.  Chest x-ray shows a moderate-sized left pleural effusion.  Which of the following is the most likely cause of the patient's current condition?


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