A Stillborn Male Fetus Is Brought to Autopsy for Evaluation

question 422

Multiple Choice

A stillborn male fetus is brought to autopsy for evaluation.  The fetus was delivered at approximately 36 weeks gestation to a 26-year-old woman, gravida 5 para 1 aborta 3, who received no prenatal care.  The mother came to the hospital in active labor; an ultrasound on admission revealed no fetal cardiac activity.  She had an uncomplicated vaginal delivery of the stillborn fetus, weight 2.2 kg (4.9 lb) .  The mother had a prior healthy female infant via normal vaginal delivery at 39 weeks gestation and 3 subsequent elective terminations of pregnancy.  She does not use tobacco, alcohol, or illicit drugs.  The fetus has short, bent extremities.  X-ray reveals multiple limb fractures and a hypoplastic thoracic cavity.  Which of the following is the most likely cause of these fetal abnormalities?

• A)Achondroplasia
• B)Amniotic band sequence
• C)Birth trauma
• D)Osteogenesis imperfecta
• E)Paget disease
• F)Potter sequence
• G)Vitamin D deficiency