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A 62-Year-Old Man with Hypertension and Heart Failure Comes to the Office

question 1037

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A 62-year-old man with hypertension and heart failure comes to the office for follow-up 2 weeks after hospital discharge for acute decompensated heart failure.  The patient becomes short of breath after walking 1 block or climbing a flight of stairs but does not have orthopnea, cough, or hemoptysis.  Current medications include metoprolol succinate, sacubitril-valsartan, furosemide, and spironolactone.  Blood pressure is 128/76 mm Hg and pulse is 80/min.  Oxygen saturation is 95% on room air.  Jugular venous pressure is estimated at 8 cm H2O.  Lungs are clear to auscultation, and an S3 is heard at the apex.  There is trace peripheral edema.  Echocardiography shows left ventricular ejection fraction of 30%, mild mitral regurgitation, and mild pulmonary hypertension.  The patient's serum creatinine is 1.2 mg/dL, and serum potassium is 5.0 mEq/L.  Which of the following is the best additional therapy for this patient?

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