Crystal has been vomiting for 24 hours with complaint of right lower quadrant pain. Examination is suspicious for acute appendicitis. Crystal is taken to surgery and laparoscopic appendectomy is carried out. Pathological diagnosis is consistent with acute appendicitis. 
Definitions:
Chromosome 21
The smallest human chromosome, abnormalities in which can lead to Down syndrome.
Amino Acid Sequence
The order of amino acids in a protein, determining its structure and function.
Gene Duplication
The process by which a segment of DNA containing a gene is duplicated, potentially leading to genetic innovation and evolution.
Chromosome Deletion
A mutation involving the loss of a section of a chromosome, which can lead to developmental issues or diseases.
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