Why Is There a Need to Produce Okazaki Fragments on the Lagging

question 39

Multiple Choice

Why is there a need to produce Okazaki fragments on the lagging strand,but not on the leading strand of DNA?

• A)The two parental strands of DNA are antiparallel and DNA polymerase makes DNA in the 5' to 3'direction only.
• B)It is substantially more efficient to make several shorter strands rather than one longer strand of DNA.
• C)There is not enough cellular DNA ligase for bonding Okazaki fragments together if they were produced from both parental strands.
• D)By having one leading strand and one lagging strand the cell can limit the amount of DNA polymerase used for chromosomal replication.
• E)The leading strand opens first,and so Okazaki fragments are not needed.The lagging strand unwinds second resulting in the need to produce Okazaki fragments.

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