You Work in a Lab That Is Studying PiRISCs and PIWI

question 13

Multiple Choice

You work in a lab that is studying piRISCs and PIWI proteins. You have isolated piRISCs from a cell. What would be one way to identify which piRISCs are involved in cleaving TE RNA vs. those that halt transcription?

• A) One of the proteins in the pRISC that halts transcription should have a nuclear localization signal.
• B) One of the proteins in the pRISC that halts transcription should have nuclease activity.
• C) One of the proteins in the pRISC that halts transcription should have acetylation activity.
• D) One of the proteins in the pRISC that halts transcription should function as a transcription factor.

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