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Dyslipidemia Is Diagnosed in a 34-Year-Old Man

question 484

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Dyslipidemia is diagnosed in a 34-year-old man. He also has other medical conditions, like a myocardial infarction about a week ago. At the age of 48, his father suffered a myocardial infarction and passed away. Other family members have experienced hypertension and myocardial infarctions. After suffering a myocardial infarction, the patient gave up smoking and drinking. Simvastatin and cholestyramine have been started for him. Which of the following best describes the independent effects of simvastatin and cholestyramine, respectively, on hepatic cholesterol synthesis?


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