A 52-Year-Old Lady with a History of Locally Advanced Breast

question 483

Multiple Choice

A 52-year-old lady with a history of locally advanced breast cancer visits the office for follow-up. The patient has not received radiation therapy but is getting chemotherapy with trastuzumab as the main ingredient. She doesn't have any symptoms other than a little weariness. The heart rate is regular at 85 beats per minute and blood pressure is 120/72 mm Hg. The patient is afebrile. A 40% left ventricular ejection fraction is seen on transthoracic echocardiography, with no signs of valvular disease. Prior to the start of chemotherapy, a cardiac evaluation was performed and found to be normal. Which of the following pathologic findings is most likely to be present in this patient's heart?

• A)Abnormal protein accumulation in the extracellular space
• B)Focal ischemic cardiomyocyte necrosis
• C)Myocardial tumor cell infiltration
• D)Patchy cardiomyocyte necrosis with diffuse myocardial fibrosis
• E)Reduced cardiomyocyte contractility with no fibrosis

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Definitions:

Lowest-priority Code

In computing or digital communications, a code assigned to processes or signals deemed least critical, indicating they are to be executed or addressed last.

Dexron II

A type of automatic transmission fluid specified by General Motors, suitable for use in vehicles requiring this particular grade.

CX Family

Generally refers to a series or family of vehicles, products, or technologies, often characterized by a common design, features, or purpose. Without more context, it's too broad to specify further.

WT Transmission

WT Transmission, if referring to a specific technology or model, could denote a specialized transmission system; however, without further context, the exact nature of "WT Transmission" is unclear.