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A 3-Year-Old Boy Is Brought to the Office with 5

question 124

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A 3-year-old boy is brought to the office with 5 days of productive cough and fever.  Examination shows a tachypneic, ill-appearing child with rales over the right lower lung.  Chest x-ray reveals right lower lobe pneumonia.  The boy is admitted to the hospital for intravenous antibiotics.  Review of his medical history shows 4 prior pneumonias, and his weight is at the third percentile.  Further testing demonstrates high sweat chloride content, and genetic sequencing shows a mutation in a transmembrane protein.  Which of the following best describes the dysfunctional transmembrane protein causing this patient's disease?


Definitions:

African Slaves

Individuals from Africa who were forcibly transported to the New World as part of the transatlantic slave trade and subjected to lifetime servitude.

Legal Rights

Entitlements or permissions granted by law to individuals or entities, allowing them to perform certain actions or be treated in specific ways.

Homeland Rituals

Traditional ceremonies or practices carried out by a group of people in their native country or region.

Enslaved Africans

Individuals of African descent who were forcibly brought to and held in bondage in the Americas and other colonies, playing a central role in the transatlantic slave trade.

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