Discuss Trends in the Annual Mortality and Case Fatality of VTE

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The Answer is In a prospective analysis of death certificate in the United States during 1979-1998, the age-adjusted annual mortality rates from PE declined by 51% during the 20-year study period, from 191 per million in 1979 to 94 per million in 1998, decreasing by 56% in men and 46% in women. PE patients hospitalized in stable condition (not in shock and not ventilator-dependent) had markedly lower case fatality compared to those in unstable condition (in shock or ventilator-dependent). In 2008, the case fatality in stable VTE patients was 6% compared to 36% in unstable patients. Mortality and case fatality are increased by the presence of comorbid conditions, e.g. the case fatality is over 50% higher in patients with active cancer versus those without cancer.

Discuss Trends in the Annual Mortality and Case Fatality of VTE

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