It Was Originally Thought That the DNA Polymerase Machinery Moves

question 45

Essay

It was originally thought that the DNA polymerase machinery moves along the DNA in the manner analogous to a train on a track. Current evidence indicates that the polymerizing machinery is instead stationary, and DNA strands are pumped through the complex. What advantages does this stationary machinery have?

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Definitions:

Statistical Probability

The likelihood of an event occurring based on a mathematical model, often expressed as a number between 0 and 1.

T-test

A statistical test used to compare the means of two groups to determine if they come from the same population.

Alpha

A predetermined threshold in hypothesis testing that defines the probability of making a Type I Error, usually set at 0.05, indicating a 5% risk of false positive.