One of the Earliest and Most Profound Changes Found in Patients

question 26

Multiple Choice

One of the earliest and most profound changes found in patients with Alzheimer's disease is

• A) death of substantia nigra dopaminergic neurons.
• B) death of striatal GABAergic neurons.
• C) death of raphe serotonergic neurons.
• D) loss of the subthalamic neurons.
• E) degeneration of the basal forebrain cholinergic neurons.

---

Definitions:

Obsession

A persistent, intrusive, and unwanted thought, urge, or image that causes significant anxiety or distress.

Compulsion

An uncontrollable urge to perform an act repeatedly, often a symptom of obsessive-compulsive disorder (OCD).

Obsessive-Compulsive Disorder

A mental disorder characterized by unwanted repetitive thoughts (obsessions) and/or actions (compulsions).

Psychogenic Paralysis

A loss of motor function without a physiological cause, arising from psychological factors.