How Is G Protein-Mediated Signaling Terminated

question 19

Multiple Choice

How is G protein-mediated signaling terminated?

• A) Desensitization of the G protein-coupled receptor terminates the signaling previously initiated by active G proteins.
• B) Hydrolysis of GDP to GTP by the endogenous GTPase activity of the α-subunit leads to reassociation of the αβγ-complex, terminating the response.
• C) Exchange of GDP for GTP by the endogenous GTPase activity of the α-subunit leads to reassociation of the αβγ-complex, terminating the response.
• D) Exchange of GTP for GDP by the endogenous GTPase activity of the α-subunit leads to reassociation of the αβγ-complex, terminating the response.
• E) Hydrolysis of GTP to GDP by the endogenous GTPase activity of the α-subunit leads to reassociation of the αβγ-complex, terminating the response.

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Definitions:

Materials Quantity Variance

The difference between the actual amount of materials used in production and the standard amount expected to be used, multiplied by the standard cost per unit.

Raw Materials Price

The cost of raw materials required in the manufacturing process, a critical factor in the overall production cost and pricing strategy.

Variance

The difference between a planned, budgeted, or standard amount and the actual amount incurred or realized.

Revenue Variance

The difference between actual revenue earned and expected revenue, often used in budgeting and financial analysis.