Which of the Following Tests Would Be Effective at Determining

question 32

Multiple Choice

Which of the following tests would be effective at determining if a transmitter action was mediated by a G protein-coupled receptor?

• A) Adding extra GTP to the cell cytoplasm to activate G protein-coupled receptors.
• B) The addition of cholera toxin to inhibit G protein-coupled receptors.
• C) The addition of GDP-β-s enhances and greatly prolongs agonist-induced activation of G protein-mediated responses.
• D) The addition of GTP-γ-s enhances and greatly prolongs agonist-induced activation of G protein-mediated responses.
• E) The addition of pertussis toxin to activate G protein-coupled receptors.

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