NMDA and AMPA Subtypes of Glutamate Receptors Are Differentially Regulated

question 53

Essay

NMDA and AMPA subtypes of glutamate receptors are differentially regulated during synaptic plasticity, with AMPA receptors moving into or out of the postsynaptic density to alter the strength of chemical transmission. Explain how these two types of receptors are localized to postsynaptic sites of transmitter release and how these localization mechanisms might explain these differences in receptor movement.

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