How Do Developmental Changes in Chloride Transporter Expression Affect GABAergic

question 54

Multiple Choice

How do developmental changes in chloride transporter expression affect GABAergic transmission?

• A) The developmental switch from NKCC1 to KCC2 allows GABA to become depolarizing.
• B) Changes in chloride transporter expression do not alter GABAergic transmission.
• C) In the immature brain, GABA transporters can transport both glutamate and GABA. The delayed expression of KCC2 promotes the substrate specificity of GABA transporters.
• D) Developmental changes in chloride transporters allow GABAergic transmission to have faster kinetics.
• E) The delayed expression of KCC2 allows GABA to evoke membrane hyperpolarization in the mature, not the immature brain.

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Definitions:

Perceptual Constancies

Perceptual constancies refer to the brain's ability to perceive objects as unchanged despite shifts in sensory input, such as changes in lighting, angle, or distance.

Scaffolding

An educational method that provides support and guidance to learners by building on their existing knowledge and skills to reach higher levels of understanding.

Sensorimotor Tests

Assessments designed to evaluate an individual's sensory (senses) and motor (movement) abilities, often used in developmental psychology.

Verbal Scores

A measure of an individual's verbal reasoning and understanding, often assessed in standardized tests.