Opening a Voltage-Gated Channel Generally Involves Which of the Following

question 17

Multiple Choice

Opening a voltage-gated channel generally involves which of the following roles for S6?

• A) Forming the ion selectivity filter in combination with S5 and the S5-S6 linker region
• B) Sensing transmembrane depolarization via its positively charged amino acids
• C) Relieving the physical constraints that block the cytoplasmic mouth of the channel
• D) Displacement within in the membrane via interactions with voltage-detecting S4
• E) Possibly none: a large body of evidence shows that activation of channel currents can occur independently of an S4-coupled gating mechanism, which casts doubt on the role of S6, too

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Definitions:

First Lady Eleanor Roosevelt

A prominent American political figure, diplomat, and activist who, as the wife of President Franklin D. Roosevelt, reshaped the role of the First Lady through her active participation in American politics and human rights advocacy.

First Lady

The title given to the wife of the President of the United States or other heads of state; she often takes part in public and ceremonial duties.

W.B. Du Bois

An influential African American sociologist, historian, and civil rights activist, co-founder of the NAACP, best known for his exploration of racial identity and critiques of segregation.