What Is the Principal Mechanism of Inactivation in Voltage-Activated Channels

question 10

Multiple Choice

What is the principal mechanism of inactivation in voltage-activated channels?

• A) Occlusion by elements of the ion channel that do not lie within the membrane
• B) S6 helix closing off the cytoplasmic mouth of the channel
• C) Displacement of S4 back to its "resting" position within the membrane
• D) Inactivation, or current "switching off," of the P-loop, possibly involving the selectivity filter
• E) Displacement f S6 back to its "resting" position within the membrane

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