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How Do Gain of Function Mutations to Scn9a (NaV 1

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How do gain of function mutations to Scn9a (NaV 1.7) lead to hyperalgesia (excessive or spurious pain)?


Definitions:

Freud's Theory

A set of psychoanalytic theories proposed by Sigmund Freud, which focus on unconscious processes, sexual and aggressive instincts, and childhood development.

Personality

The combination of characteristics or qualities that form an individual's distinctive character, influencing their behaviors and attitudes.

Gender Roles

Social and behavioral norms that are considered appropriate for individuals of a given sex within a specific culture.

Biological Aspect

Refers to the physiological and genetic characteristics of organisms, including humans, often highlighting the influence of genetics and bodily functions on behavior and health.

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