The "Whole Cell" Patch Clamp Technique

question 5

Multiple Choice

The "whole cell" patch clamp technique

• A) allows the experimenter to easily change the solution bathing the inside surface of the cell during the recording and study the activity of single voltage-gated channel currents.
• B) allows the experimenter to easily change the solution bathing the outside surface of the cell during the recording and study the activity of single voltage-gated channel currents.
• C) does not allow the experimenter to change the solution on either side of the cell, but you can study the summed activity of all voltage-gated channels in the cell (macroscopic current).
• D) allows the experimenter to easily change the solution bathing the inside surface of the cell during the recording and study the summed activity of all voltage-gated channels in the cell (macroscopic current).
• E) allows the experimenter to easily change the solution bathing the outside surface of the cell during the recording and study the summed activity of all voltage-gated channels in the cell (macroscopic current).

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Definitions:

Independent Variable

The variable in an experiment that is manipulated to observe its effect on the dependent variable.

Dependent Variable

The variable in experimental research that is measured to assess any changes in response to the manipulation of the independent variable.

Random Assignment

A method used in experiments where participants are allocated to various groups in a way that ensures each has an equal chance of being chosen, to ensure fairness and objectivity in the results.

Experimental Conditions

The controlled environments and variables manipulated by researchers to investigate causal relationships in a study.