The "Inside-Out" Patch Clamp Technique

question 29

Multiple Choice

The "inside-out" patch clamp technique

• A) allows the experimenter to easily change the solution bathing the inside surface of the membrane patch during the recording and study the activity of single voltage-gated channel currents.
• B) allows the experimenter to easily change the solution bathing the outside surface of the membrane patch during the recording and study the activity of single voltage-gated channel currents.
• C) does not allow the experimenter to change the solution on either side of the membrane patch, but you can study the activity of single voltage-gated currents.
• D) allows the experimenter to easily change the solution bathing the inside surface of the membrane patch during the recording and study the summed activity of all voltage-gated channels in the cell (macroscopic current).
• E) allows the experimenter to easily change the solution bathing the outside surface of the membrane patch during the recording and study the summed activity of all voltage-gated channels in the cell (macroscopic current).

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Definitions:

Masseter

A facial muscle that plays a major role in the chewing of food.

Orbicularis Oculi

A circular muscle that surrounds the eye socket and allows for the closing of the eyelids.

Levator Palpebrae Superioris

A muscle in the orbit of the eye responsible for raising the upper eyelid, enabling the eye to open.

Eyelid

Movable fold of skin in front of the eyeball; also called palpebra.