Visualization of B-Cell Traffic Between the Light and Dark Zones

question 7

Multiple Choice

Visualization of B-cell traffic between the light and dark zones of the germinal center has shown that they migrate far less than had been predicted.This demonstrates that

• A)the traditional model of trafficking is inaccurate.
• B)the rate of hypermutation and selection does not require extensive movement.
• C)only brief contacts by the B cells with helper T cells are needed.
• D)both the traditional model of trafficking is inaccurate and only brief contacts by the B cells with helper T cells are needed.
• E)both the rate of hypermutation and selection does not require extensive movement and only brief contacts by the B cells with helper T cells are needed.

---

Definitions:

Pearson Correlation Coefficient

A measure of the linear correlation between two variables X and Y, giving a value between +1 and -1, where 1 is total positive linear correlation, 0 is no linear correlation, and -1 is total negative linear correlation.

Sales

The action or business of selling products or services to customers.

Experience

The knowledge or mastery of an event or subject gained through involvement in or exposure to it.

Coefficient of Determination

The coefficient of determination, often denoted as R^2, measures the proportion of the variance in the dependent variable that is predictable from the independent variable(s).