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The Use of CAR Therapy Has Been a Major Breakthrough

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The use of CAR therapy has been a major breakthrough in cancer treatment.CAR stands for "Chimeric Antigen Receptor," and it is a combination of the antigen-binding domain of an antibody and the intracellular domain of the TCR.What advantage might this construct have over endogenous cellular machinery?


Definitions:

Inhibitory Role

The function of certain processes or substances in slowing down or stopping the activity of neural or biochemical pathways.

GABA

GABA, or Gamma-Aminobutyric Acid, is a neurotransmitter in the brain that plays a key role in regulating neuronal excitability and is involved in inducing relaxation and sleep.

Serotonin

A neurotransmitter in the brain that plays a critical role in mood regulation, appetite, sleep, and other bodily functions.

Dopamine

A neurotransmitter involved in reward, motivation, memory, attention, and even regulating body movements.

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