B-Cell Development Has One Checkpoint to Determine If V-DJ Rearrangement

question 35

Multiple Choice

B-cell development has one checkpoint to determine if V-DJ rearrangement has produced a successful V_H-DJ_H combination that does not recognize self.If no successful combination is produced, then the B cell will undergo apoptosis.At what point of B-cell development does this checkpoint occur?

• A)Pre-pro-B cell
• B)Early pro-B cell
• C)Late pro-B cell
• D)Late pre-B cell
• E)Immature B cell

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Definitions:

Organizational Politics

The activities and behaviors within an organization aimed at acquiring, developing, and using power and other resources to obtain one's preferred outcomes.

Resource Allocation

The process of assigning available resources, such as time, money, or personnel, to specific tasks, projects, or priorities.

Organizational Politics

The use of power and social networking within an organization to achieve changes that benefit the individual or a group, often at the expense of others.

Organizational Citizenship

Behavior by an employee that is above and beyond their basic job requirements, aimed at benefiting the overall organization.