Place the Class I Processing Pathway in the Correct Order

question 33

Multiple Choice

Place the class I processing pathway in the correct order:

• A)Peptides exported from the ER by TAP > peptides are digested by the proteasome > peptides are loaded onto class I > class I is exported to the cell surface
• B)Proteins are digested by the proteasome > peptides are imported into the ER by TAP > peptides are loaded onto MHC class I > class I is exported to the cell surface
• C)MHC class I moves from the cell surface to the lysosome by endocytosis > class I bound peptides are replaced with antigenic peptides in the lysosome > class I returns to the cell surface
• D)Proteins are degraded by TAP > peptides are imported into the lysosome by the proteasome > peptide-MHC class I complexes are exported to the cell surface
• E)MHC class I is transported to the ER by TAP > proteins in the ER are degraded into peptides by the proteasome > peptides bind MHC class I in the ER, and the complex is exported to the cell surface

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Definitions:

Flexible Equipment

Machinery or tools designed to be easily adapted to a broad range of tasks or to accommodate changes in production.

Rapid Changeovers

Techniques and practices implemented to reduce the time and effort required to switch a production line or system from making one product variant to another.

Mass Customization

A manufacturing approach that combines the efficiency of mass production with the ability to customize products to meet individual customer preferences.

Repetitive Process

A production process in which the same sequence of operations and tasks are repeated over and over to produce identical or very similar products.