Place the Class I Processing Pathway in the Correct Order

question 33

Multiple Choice

Place the class I processing pathway in the correct order:

• A)Peptides exported from the ER by TAP > peptides are digested by the proteasome > peptides are loaded onto class I > class I is exported to the cell surface
• B)Proteins are digested by the proteasome > peptides are imported into the ER by TAP > peptides are loaded onto MHC class I > class I is exported to the cell surface
• C)MHC class I moves from the cell surface to the lysosome by endocytosis > class I bound peptides are replaced with antigenic peptides in the lysosome > class I returns to the cell surface
• D)Proteins are degraded by TAP > peptides are imported into the lysosome by the proteasome > peptide-MHC class I complexes are exported to the cell surface
• E)MHC class I is transported to the ER by TAP > proteins in the ER are degraded into peptides by the proteasome > peptides bind MHC class I in the ER, and the complex is exported to the cell surface

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Definitions:

Catechist

An instructor of the principles of Christian religion, especially one using a catechism to teach.

State of Grace

A condition of being free from sin in the context of religious doctrine, or a period of flourishing or supreme excellence.

Protestant Ethic

A concept in sociology asserting that the values of hard work, thrift, and efficiency in one's worldly calling are influenced by Protestant faiths.

Frugality

The quality of being economical with resources or expenses; prioritizing saving and avoiding waste.