At Which Point in the Variable Segments Does the RAG1/2

question 6

Multiple Choice

At which point in the variable segments does the RAG1/2 complex introduce a single-strand break into the DNA during somatic rearrangement?

• A)Between the coding region and the conserved heptamer
• B)Between the conserved heptamer and the 12-bp spacer
• C)Between the 23-bp spacer and the conserved nonamer
• D)Between the nonamer and 12-bp spacer
• E)None of the answers are correct.

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