What Is the Central Mechanism for Establishing Self-Tolerance

question 8

Multiple Choice

What is the central mechanism for establishing self-tolerance?

• A)Self-reactive T cells and B cells are killed during development.
• B)Individuals that have immune systems that respond to self-antigens do not survive to reproduce.
• C)Immune cells that react to self-antigens are turned off when they recognize self-tissues.
• D)Certain immune suppressive cytokines are maintained in tissues to dampen auto reactive immune responses.
• E)Peripheral tissues have mechanisms to kill T or B cells that respond to them.

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The probability of event A occurring given that event B has already occurred.

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