Pathogenesis of Human Prion Disease Includes Which of the Following

question 39

Multiple Choice

Pathogenesis of human prion disease includes which of the following?

• A) during disease a conformational change in protein structure from 3% Beta-sheets to 43% Beta sheets occurs
• B) prions are degraded by host cell proteases
• C) neurons in the CNS become abnormally dense
• D) PrP^c prion protein induces conformational change in PrP^sc proteins spreading the damage

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