Pathogenesis of Human Prion Disease Includes Which of the Following

question 39

Multiple Choice

Pathogenesis of human prion disease includes which of the following?

• A) during disease a conformational change in protein structure from 3% Beta-sheets to 43% Beta sheets occurs
• B) prions are degraded by host cell proteases
• C) neurons in the CNS become abnormally dense
• D) PrP^c prion protein induces conformational change in PrP^sc proteins spreading the damage

---

Definitions:

Market Rate of Interest

The prevailing rate at which interest is paid by borrowers for loans or earned by investors for deposit accounts, typically influenced by the supply and demand for money in the economy.

Semiannually

Occurring or calculated twice a year, typically used in the context of bond interest payments or other financial assessments.

Market Rate of Interest

The prevailing rate of interest available in the market for investments of comparable risk and term.

Bond Indenture

A legal contract outlining the terms and conditions between the bond issuer and the bondholders.