An Active Case of Tuberculosis Has to Be Treated with a Multidrug

question 133

Multiple Choice

An active case of tuberculosis has to be treated with a multidrug approach. Which of the following list of antimycobacterial agents commonly prescribed is matched with its mechanism of action? (Select all that apply)

• A) Rifampicin/inhibit RNA polymerase
• B) Isoniazid/ inhibits mycolic acid synthesis leading to cell wall damage and cell death
• C) Pyrazinamide/converted to a base inside the cell causing pH to rise to 10 thereby inhibiting growth
• D) Ethambutol/inhibits mycolic acid synthesis leading to cell wall damage and cell death

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