How Does HHV-8 Infection in an HIV+ Patient Cause a Malignancy

question 61

Multiple Choice

How does HHV-8 infection in an HIV+ patient cause a malignancy like Kaposi's sarcoma?

• A) HHV-8 is a protovirus.
• B) HHV-8 converts normal cells to malignant cells recognized as foreign by a healthy person's immune system and destroyed. The compromised immune system of an HIV patient prevents this from happening and life-threatening Kaposi's sarcoma develops.
• C) HIV infection of the patient's T_H cells enhances their activity, triggering the development of Kaposi's sarcoma by HHV-8.
• D) HHV-8 and HIV co-infect T_H cells, causing them to mutate into the malignant cells of Kaposi's sarcoma.

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