A Cortical Neuron Is Cultured in the Presence of a Sodium

question 3

Multiple Choice

A cortical neuron is cultured in the presence of a sodium channel blocker (TTX) for two days. Assuming that synaptic scaling occurs at a relatively constant rate, what would be the most reasonable prediction for the average EPSC after 24 hours in response to stimulation?

• A) Less than 100% of control conditions.
• B) About 150% of control conditions.
• C) Greater than 192% of control conditions.
• D) No EPSCs would be observed after 24 hours.

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