Use This Description to Answer the Following Questions

question 11

Multiple Choice

Use this description to answer the following questions.
A major group of G protein-coupled receptors contains seven transmembrane α helices. The amino end of the protein lies at the exterior of the plasma membrane. Loops of amino acids connect the helices either at the exterior face or on the cytosol face of the membrane. The loop on the cytosol side between helices 5 and 6 is usually substantially longer than the others.
-If you wish to design an experiment to block the G protein-coupled receptor interaction, the block would preferentially affect which of the following?

• A) the exterior (cytoplasmic) end of the receptor
• B) the cytosolic end of the receptor
• C) the phospholipid's transmembrane domain
• D) the amino acid sequence in the binding site for the G protein
• E) the amino acids in the binding site for the transduction molecules

---

Definitions:

Hawaiian Swordtail Crickets

A species or group of crickets native to Hawaii, known for unique traits such as their distinctive tail-like appendages.

Reproductive Barrier

Biological features or mechanisms that prevent species from breeding with each other, maintaining species distinctiveness.

Gametic Incompatibility

Occurs when sperm or pollen from one species fails to penetrate and fertilize the egg or ovule of another species.

Reproductive Isolation

A collection of mechanisms, behaviors, and physiological processes that prevent the members of two different species from producing offspring, or ensure any offspring are sterile.