Use the Following Information to Answer the Next Few Questions

question 43

Multiple Choice

Use the following information to answer the next few questions.
Poliovirus is a positive-sense RNA virus of the picornavirus group. At its 5' end, the RNA genome has a viral protein (VPg) instead of a 5' cap. This is followed by a nontranslated leader sequence, and then a single long protein coding region (~7,000 nucleotides) , followed by a poly-A tail. Observations were made that used radioactive amino acid analogues. Short period use of the radioactive amino acids result in labeling of only very long proteins, while longer periods of labeling result in several different short polypeptides.
-What part of the poliovirus would first interact with host cell ribosomes to mediate translation?

• A) the poly-A tail
• B) the leader sequence
• C) the VPg protein
• D) the AUG in the leader sequence
• E) the AUG at the start of the coding sequence

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Definitions:

Plantwide Overhead Rate

A single overhead rate calculated by dividing total manufacturing overhead costs by the total measure of activity across the entire plant.

Manufacturing Overhead

All manufacturing costs that are not directly traceable to the product being produced, including costs related to indirect materials, indirect labor, and other indirect expenses.

Activity-Based Costing

An accounting method that assigns costs to products or services based on the activities required to produce them, aiming for more accurate cost allocation.

Idle Capacity

Unused production capability in a given period, often resulting in inefficiency and increased costs.