Use the Following Information as Background for the Next Few

question 54

Multiple Choice

Use the following information as background for the next few questions.
Immunodeficiencies can be genetic in origin,and two examples are Bruton's agammaglobulinemia,an X-linked disorder,and DiGeorge syndrome,caused by a deletion from chromosome 22.Bruton's disorder results in underdeveloped B cells,whereas DiGeorge syndrome results in a missing or seriously underdeveloped thymus.
-Assume that a DiGeorge syndrome-like phenotype was produced in a specific "gene-knockout" mouse,one lacking expression of HA3,a Hox gene known to be involved in developmental regulation in the mouse.
The phenotype of the HA3 knockout can be ascertained by

• A)a bone marrow biopsy.
• B)an assay for environmental agents known to cause birth defects.
• C)a chest X-ray.
• D)the measurement of the proportion of CD4 cells to total lymphocytes.
• E)an autopsy examination of the adrenal glands.

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Definitions:

Hysterotomy

A surgical procedure that involves making an incision in the uterus, often as part of a cesarean section.

Ovulation

The phase in the menstrual cycle when an ovary releases an egg, making it available for fertilization by sperm.

Mittelschmerz

A term used to describe the pain associated with ovulation, occurring midway through the menstrual cycle.

Menstruation

A natural, monthly process occurring in female reproductive systems where the lining of the uterus is shed through the vagina.