There Are Several Toxins That Interfere with Synaptic Transmission

question 8

Multiple Choice

There are several toxins that interfere with synaptic transmission. Botulism toxin, for example, interferes with the fusion of acetylcholine-containing vesicles with the membrane of the axon bulb. This would result in which one of the following?

• A) blockage of Ca²⁺ diffusion into the axon
• B) slow diffusion of the neurotransmitter across the synaptic cleft
• C) inability of neurotransmitter to bind the receptor on the postsynaptic membrane
• D) blocking of neurotransmitter release by the presynaptic membrane
• E) hyperpolarization of the postsynaptic membrane

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