The Key Difference Between the First and Second Generation Antihistamines

question 16

Multiple Choice

The key difference between the first and second generation antihistamines is that:

• A) with second generation antihistamines, lower dosages are required for the same therapeutic effect.
• B) second generation medications have more undesirable side effects.
• C) the first generation antihistamines are more lipophilic and therefore cross the blood-brain barrier (BBB) causing central nervous system effects.
• D) the first generation antihistamines are more lipophobic and therefore cross the blood-brain barrier (BBB) causing central nervous system effects.

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Definitions:

Contribution Margin

The amount remaining from sales revenue after variable expenses are deducted, indicating how much revenue is contributing to fixed expenses and profit.

Labor Hours

A measure of the amount of work or effort in terms of hours spent by workers in producing goods or providing services.

Profitable Use

The utilization of resources or assets in a way that generates a financial gain.

Fixed Manufacturing Overhead

Costs in manufacturing that do not vary with the level of production, such as salaries of supervisors and rent of the factory.